He graduated from the Department of Agricultural Chemistry, Taiwan University in 1967. In 1974, he received his doctoral degree from the University of Chicago, and then went to the University of Minnesota to do postdoctoral research. In 1988, he became a professor in the Department of Chemistry, Taiwan University. He served as the Distinguished Research Fellow, Director of the Institute of Chemistry, Academia Sinica, Taiwan, and Distinguished Chair Pro-fessor at National Taiwan University.